The same principles apply to other kinds of interaction – restrooms for example. At a new (and mostly magnificent) medical research facility poor interface design for the restrooms makes using them confusing and frustrating.
The main problem is that you see this sign...
The problem is that you are greeted with this....
Only if you proceed much farther into this area, which turns out to be a kind of vestibule, with restrooms at either end, do you get any indication that there is also a men's room: